The Loose Cannon! - Cutaneous Manifestation of Langerhans Cell Histiocytosis

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Cutaneous Langerhans cell histiocytosis.

A 5 year old boy presented with papules and nodules on face, chest and upper extremities and seborrhea of scalp for 4 years. Some old healed scars were also present. Lesions were pruritic to begin with but were non-itchy. Examination revealed erythematous plaques and nodules on face and upper limbs. Lesions were more marked on forehead, cheek (Fig. 1) and dorsum of hands. There were contracture...

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Langerhans cell histiocytosis

Introduction: Langerhans cell histiocytosis (LCH), which was previously known as histiocytosis X, refers to a group of lesions that stimulate uncontrolled proliferation of cells. The purpose of this case was to report and describe a LCH case with mandibular bone involvement in a 2.5-year-old boy. Case reports: A 2.5 years old boy with LCH of mandibular jaw who has been treated by surgical inter...

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Langerhans cell Histiocytosis: Report of a case with cutaneous lesions with favorable response to oral Thalidomide

We report of a 29-year-old man presented with yellow-red, scaling papules on the skin of scalp, retro-auricular folds, inguinal, axillary, chest and abdomen. The lesions had a poikilodermatious appearance in some areas, such as trunk. The patient also had diabetes insipidus and skull osteolytic lesions. The diagnosis of langerhans cell histiocytosis (LCH) was suggested based on H and E staining...

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Current Treatment Strategy in Langerhans Cell Histiocytosis

Langerhans cell histiocytosis (LCH) is a rare disorder described as three different entities including eosinophilic granulomaof bone, the Hand-Schuller-Christian syndrome, and Letterer-Siwe disease. LCH is currently classified into singlesystem LCH, and multisystem LCH. Patients with single system LCH have an excellent prognosis, and are mostlytreated with local therapy. Multisystem LCH is subd...

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ژورنال

عنوان ژورنال: Journal of Clinical Case Reports

سال: 2018

ISSN: 2165-7920

DOI: 10.4172/2165-7920.10001160